A wooden pergola structure with a concrete base, surrounded by a chain-link fence and lush greenery.

Lake Nona Vacations from $232

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Your Lake Nona Vacation

Experience all the wonderful things this neighborhood has to offer with a tailor-made Lake Nona vacation package. However you imagine spending your days here, you'll find endless opportunities for relaxation, fun and adventure. Start your trip to Lake Nona by visiting nearby attractions such as University of Central Florida College of Medicine, Sanford-Burnham Medical Research Institute and David Leadbetter Golf Academy. Expedia can put your travel plans into action. Book your dream Lake Nona vacation today.

The Latest Lake Nona Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 10 - Jan 16

    Palazzo Lakeside Hotel + Flight

    Kissimmee
    6 nights
    3.0 star property
    8.4/10 - Very good (5,379 reviews)
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - BOS • Nonstop
    $395
    $232
    per traveler
    found 1 day ago
    Palazzo Lakeside Hotel
  • Jan 10 - Jan 16

    Margaritaville Cottages Orlando by Vstays with H2O Waterpark + Flight

    Kissimmee
    6 nights
    4.0 star property
    9.2/10 - Wonderful (1,000 reviews)
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - BOS • Nonstop
    $1,799
    $781
    per traveler
    found 1 day ago
    Margaritaville Cottages Orlando by Vstays with H2O Waterpark
  • Jan 10 - Jan 16

    Seasons Kissimmee - Orlando - Lake Buena Vista South, Florida Resort + Flight

    Kissimmee
    6 nights
    2.0 star property
    9.0/10 - Wonderful (4,096 reviews)
    "Nice spot. To enjoy comfort peace and quiet. Coffee each morning was a bonus"
    Reviewed November 7, 2026
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - BOS • Nonstop
    $830
    $365
    per traveler
    found 1 day ago
    Seasons Kissimmee - Orlando - Lake Buena Vista South, Florida Resort
  • Jan 10 - Jan 16

    The Delaney Hotel + Flight

    South Orange
    6 nights
    3.5 star property
    9.6/10 - Exceptional (1,244 reviews)
    "Great Hotel. Well Located and the staff is very friendly!"
    Reviewed November 6, 2026
    Roundtrip • Boston (BOS) - Orlando (MCO)
    BOS - MCO • Nonstop MCO - BOS • Nonstop
    $1,179
    $580
    per traveler
    found 1 day ago
    The Delaney Hotel
  • Jan 22 - Jan 26

    Westgate Cocoa Beach Resort + Flight

    Cocoa Beach
    4 nights
    4.0 star property
    8.6/10 - Excellent (577 reviews)
    "Great place!"
    Reviewed November 2, 2026
    Roundtrip • New York (NYC) - Orlando (MCO)
    LGA - MCO • Nonstop MCO - LGA • Nonstop
    $1,090
    $548
    per traveler
    found 1 day ago
    Westgate Cocoa Beach Resort

Where to stay in Lake Nona

Find the best Lake Nona areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona
Learn more about Lake Nona

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Reunion

The waterparks and pristine golf courses are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

Discover the most popular places to visit in Lake Nona

What to do near Lake Nona

Lake Nona Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.